A 50-year-old male presents with fatigue and abdominal distension for 6 months. Physical examination shows anemic appearance and liver palpable 1 cm below the costal margin. Lab results: Hb 70g/L, WBC 250x10<sup>9</sup>/L with predominance of myelocytes and metamyelocytes, PLT 400x10<sup>9</sup>/L. NAP score is reduced. The most likely diagnosis is: