A 33-year-old female presents with bilateral lower extremity edema for 1 month. She has a 3-year history of chronic hepatitis B. Urinalysis shows proteinuria and red blood cells 20 per HPF. 24-hour urinary protein quantification is 4.0 g, plasma albumin 28.5 g/L, serum creatinine 90 μmol/L, and both HBsAg and HBeAg are positive. The most likely diagnosis is: