A 30-year-old male presents with recurrent periorbital edema and nocturia for 2 years, BP 160/100 mmHg, urinary protein (+), RBC 5–10/HPF, granular casts 1–2/HPF, serum creatinine 145 μmol/L, hemoglobin 85 g/L, serum albumin 32 g/L. Which of the following clinical findings is LEAST relevant for diagnosis?