A 35-year-old male presents with hypertension, visual disturbances, nausea and vomiting. Examination: BP 210/120 mmHg, heart border enlarged to the lower left, Hb 65g/L, urinary protein (+++), RBC 5-10/HPF, Cr 760 μmol/L, ultrasound shows bilateral kidney shrinkage, retinal hemorrhages and exudates. No prior history of kidney disease. The most likely diagnosis is: