A 58-year-old male presents with recurrent cough and sputum production for 15 years, and palpitations and dyspnea for 3 years. Physical examination reveals hyperresonance on percussion, diminished breath sounds, basal rales/crackles, prominent apical impulse at the xiphoid process with a 3/6 systolic murmur, and accentuated P2 sound in the pulmonary valve area. The most likely diagnosis is: