Thymine dimers interfere with DNA synthesis by

Acausing a break in the DNA template strand
Bforming apurinic/apyrimidic sites in DNA strands
Ccausing bends and kinks, affecting the DNA double helix, thereby hindering replication and transcription
Dforming negative supercoils between the two DNA strands

Correct answer: C. causing bends and kinks, affecting the DNA double helix, thereby hindering replication and transcription

Thymine dimers cause structural distortions in the DNA molecule by creating bends and kinks. These distortions interfere with the normal processes of DNA replication and transcription, making option C the correct answer.

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