Which of the following statements about the interaction between nucleic acids and proteins is incorrect?
Correct answer: D. DNA bases cannot form hydrogen bonds with proteins
Nucleic acids, such as DNA, can indeed interact with proteins through various mechanisms. The major groove of DNA can accommodate alpha-helices, DNA bases and pentose sugars can engage in hydrophobic interactions, and phosphate groups can form ionic bonds with protein side chains. However, nucleic acid bases do have the ability to form hydrogen bonds with proteins under certain conditions.