NCERT Biology Class 12, Chapter 5

Mutation and gene expression NEET Biology MCQ

Last updated: July 30, 2026

Reviewed by MedQGo Editorial Team | Last updated: July 30, 2026

Which of the following is not a mechanism for activating proto-oncogenes?

ALoss of heterozygosity

BPromoter region hypermethylation

CGene mutation

DChromosomal translocation

Correct answer: B. Promoter region hypermethylation

Proto-oncogenes can be activated through gene mutations, chromosomal translocations, or loss of heterozygosity. However, promoter region hypermethylation typically silences genes rather than activates them.

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