In an in vitro experiment, gradually replacing the Na^+ in the bathing solution with glucose, the amplitude of the action potential in a neuron or nerve fiber will

Agradually increase
Bgradually decrease
Cremain unchanged
Dfirst increase then decrease

Correct answer: B. gradually decrease

The presence of Na^+ ions is crucial for the generation and propagation of action potentials. Gradual replacement with glucose, which does not contribute to the depolarization process, will reduce the amplitude of the action potential.

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